Dystrophic phenotype induced in vitro
نویسندگان
چکیده
Susan C. Brown1,*, Ariberto Fassati1,*,‡, Linda Popplewell1, Anton M. Page1, Michael D. Henry2, Kevin P. Campbell2 and George Dickson1,§ 1Division of Biochemistry, School of Biological Sciences, Royal Holloway College, University of London, Egham, Surrey TW20 0EX, UK 2Howard Hughes Medical Institute and Department of Physiology and Biophysics and Department of Neurology, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA
منابع مشابه
Systemic administration of IGF-I enhances oxidative status and reduces contraction-induced injury in skeletal muscles of mdx dystrophic mice.
The absence of dystrophin and resultant disruption of the dystrophin glycoprotein complex renders skeletal muscles of dystrophic patients and dystrophic mdx mice susceptible to contraction-induced injury. Strategies to reduce contraction-induced injury are of critical importance, because this mode of damage contributes to the etiology of myofiber breakdown in the dystrophic pathology. Transgeni...
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تاریخ انتشار 1998